| Vitamin E deficiency may be associated with a
discrete syndrome. Causes
Deficiency of vitamin E may be caused due to selective malabsorption of the vitamin or
when recessive mutation causes vitamin E deficiency and ataxia*. More commonly intestinal
fat malabsorption can cause deficiency of all fat-soluble vitamins.
* Failure of muscular coordination
Signs and symptoms
The manifestations of the deficiency include, gait disturbance, fluid retention,
anaemia. In adults, apathy, inability to concentrate and loss of balance are the common
symptoms.
Prevention and treatment
Treatment 50 to 100 I.U. per day orally is most effective when initiated early in the
course of the disease.
Vitamin E
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